Niacin supplementation reverses Fatty Liver Disease
New findings from UNCG Center for Translational Biomedical Research
August 28, 2014
Zhanxiang Zhou, PhD, with the UNC Greensboro Center for Translational Biomedical Research at the NC Research Campus in Kannapolis, published new findings in the July 2014 edition of Alcoholism: Clinical and Experimental Research that established a connection between niacin supplementation and lowering lipid levels in the liver.
ZhouZhou researches the pathology of and potential treatments for alcohol-induced fatty liver disease. His recent paper, “Dietary Nicotonic Acid Supplementation Ameliorates Chronic Alcohol-induced Fatty Liver in Rats,” demonstrated in an animal model that niacin supplementation reduced liver lipids significantly in only eight weeks by accelerating fatty acid oxidation, which is the breakdown of fatty acids. His study also showed that niacin supplementation remarkably increased the blood adiponectin level, an adipose secreted hormone, which stimulates fatty acid oxidation in the liver.
Alcohol- and non-alcohol induced fatty liver disease are the leading cause of liver damage and often progress to serious medical conditions such as steatohepatitis, cirrhosis or liver cancer.