Posted on September 22, 2025

Dr. Gideon Wasserberg holds a box up and looks inside.

North Carolina is experiencing a surge in Lyme disease cases, and a new surveillance study from UNC Greensboro (UNCG) reveals that the primary vector of the bacteria that cause Lyme disease, the blacklegged tick (Ixodes scapularis), has been spreading into areas previously considered low risk.

“Currently, 16 states, mostly in the Northeast, mid-Atlantic, and upper Midwest, account for 95% of the reported LD cases,” says Dr. Gideon Wasserberg, a biology professor at UNCG and one of the research project leaders. “However, low-incidence states to the south and west, including North Carolina, have experienced an increase in the number of reported Lyme disease cases since the early 2010s.”

With funding from Centers for Disease Control, administered by the North Carolina Department of Health and Human Services, researchers from UNCG, North Carolina State University, and Appalachian State University conducted a five-year, statewide survey of blacklegged ticks and the pathogens they often carry.

Eastern Piedmont and the Coastal Plain, where blacklegged ticks and human Lyme disease cases have been historically noted, saw little change in tick density in comparison. 

In the new study, ticks from the Blue Ridge Mountains were also more likely to carry Borrelia burgdorferi, the bacteria responsible for most cases of Lyme disease, compared to ticks from the Piedmont and Coastal Plain. 

“Our analyses indicate that these ticks and the bacteria they carry moved into the Blue Ridge Mountains of North Carolina from southwestern Virginia over the last 10 years, travelling along the Appalachian Mountains,” says Wasserberg.

The researchers say the findings have important implications for public health.

Now a research scientist at the New Jersey Department of Health, Garshong participated in much of the study as a doctoral student in Wasserberg’s lab at UNCG.


by Brian Clarey and Sangeetha Shivaji
Photography by Sean Norona

Learn more about Dr. Wasserberg’s work in UNCG Research Magazine

Garshong ’23 Ph.D., Wasserberg, and graduate student Noah Holland collect ticks in the field.

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